Superb Probiotic Substitute from Russia
by Dr. James Howenstine, MD
Having healthy bacteria in the intestinal tract has long been regarded
as a prerequisite for good health. Older civilizations promoted this with
fermented substances such as sauerkraut, unpasteurized yogurt, kombucha
(fermented tea, mushroom, sugar) and raw milk. The lining surface of the
intestines constitutes the largest immune structure in the human body.
More than 50% of the body's vital immune cells reside in the intestinal
lining. Bacteria in the intestines improve the function of the whole intestinal
tract, protect our body against pathogenic bacteria by blocking their
entrance into the body,, create needed vitamins and hormones and maintain
the chemical balance of the intestinal tract.
Healthy intestinal bacteria stimulate the immunologic function of the
spleen, create a protective barrier against harmful organisms by coating
the intestinal lining, compete with harmful bacteria for nutrients which
curtails growth of bad bacteria, produce the beneficial natural antibiotic
substances (acidophillin, bifidin, hydrogen peroxide), increases the bioavailability
of calcium aid by fermenting soluble fiber are able to supply 5 to 10%
of the body's energy needs.
The normal balance of healthy bacteria is 85% good and 15% bad. This
ratio is now reversed for most Americans.
Death of many healthy intestinal bacteria damages the function of the
lining membrane of the intestine. When this membrane has been injured
partially digested proteins, toxins, undigested food particles and infectious
substances can penetrate the normally protective intestinal lining.. These
"foreign" substances can initiate allergic responses to food
, start infectious problems and lead to autoimmune reactions against the
"foreign substances".. Unfortunately healthy intestinal bacteria
can be killed by many commonly experienced exposures:
- Courses of antibiotics kill healthy intestinal bacteria leaving dangerous
anaerobic bacteria, yeast, fungi and mycoplasma to proliferate replacing
the desirable intestinal bacteria. This may result in deterioration
in immune defenses permitting new infectious diseases to occur easily
and frequently.
- Chlorine used to sterilize drinking water kills healthy bacteria
- Non steroidal anti-inflammatory bacteria kill healthy intestinal bacteria.
These drugs are widely used in inflammatory diseases.
- Fluoride used in water for its supposed ability to prevent cavities
is toxic to the good intestinal bacteria.
Because of the beneficial effects of having healthy intestinal bacteria
many persons take probiotics. Probiotic substances contain living bacteria
supplied in capsules and other novel forms of administration, that are
thought to supply the intestinal tract with a large quantity of desirable
living bacteria. All these probiotic products suffer from the same problem.
It is impossible to know whether these products are actually delivering
any living good bacteria to the intestines. Careful research studies have
revealed that probiotic products often contain no living bacteria or so
few that they could not be expected to bring about any meaningful benefit
to health. Obviously the consumer may be wasting his money.
Some probiotics contain bacteria not normally found in the intestines.
When these products are stopped these foreign bacteria are rapidly replaced
by the common intestinal flora thus stopping any further benefits from
the added bacteria.
A retired US pharmacist, Dr. Robert Sichel, had a daughter with a serious
Hepatitis C infection. Dr. Sichel's search for something that might help
her led him to a Russian product derived from lactobacillus Bulgarica.
When his daughter took this Russian preparation her blood viral load fell
from 200,000 to zero and blood chemistries became normal allowing a complete
recovery to occur.
European research had discovered that fragments of certain bacterial
cell walls were actually more effective in stimulating immune health than
were living bacterial cells. The potency of this nonbacterial Russian
product is continuous not steadily deteriorating as are probiotic preparations
whose bacteria are constantly dying in their capsules before use. Because
these bacterial cell fragments[1] are not living bacteria they can be
easily shipped and stored without refrigeration. Bacterial cell wall fragments
have proven to be a more effective stimulus to the immune system than
are living bacteria.
Russia experienced a major public health catastrophe when bacillus anthrax
at a bio-warfare facility in Sverdlosk was accidentally released in 1979
into the air. An estimated 100 persons died and many more were chronically
ill from this infection. Another major health problem occurred after the
nuclear plant meltdown at Chernobyl. These problems led the State Scientific
Research Institute of Highly Pure Bio-preparations in St. Petersburg to
initiate a program to find a protective agent against bio-warfare infections
and radiation injury, that was promptly effective, safe and inexpensive.
They screened 600 substances before deciding that a species of lactobacillus
bulgaricus cell wall appeared to meet all criteria. This original bacterial
species was isolated from raw milk on a farm near St. Petersburg.
Subsequent research by Vivolac Cultures Corporation of Indianapolis,
Indiana revealed that the Russian product was actually lactobacillus rhamnose.
In the process of growing this bacillus in a more nutritious media and
using longer fermentation times a better product was created that was
at least twice as effective as the Russian product. The new product was
named Del Immune V (DIV). These lactobacilli are used to create cheese
and yogurt. DNA analysis insures that every batch of Del-Immune V is identical.
The shelf life is two years. Del-Immune V usually begins to act within
6 hours.
Why Does Lactobacilli Rhamnose Work?
The special strain of L. rhamnose contains peptidoglycans, lipopolysaccharides
and other cell wall fractions that markedly enhance immunity. The peptidoglycans
and lipopolysaccharides strongly stimulate the formation of new mucosal
and circulating lymphocytes as well as increase cytokines such as tumor
necrosis factor-alpha (TNF-alpha) and interleukin 2 (IL-2). TNF-alpha
and Il-2 are key substances in breaking tumor cell walls and killing invading
infectious pathogens. The immune enhancing factors in Lrhamnose seem to
normalize the production of TFN-alpha and IL-2 so destructive injury from
excess cytokines does not occur.
Bulgaria began using cell wall l.bulgaricus in 1988. Absenteeisms due
to infectious illness was a problem then. When workers were given L. bulgaricus
prophylacticly absenteeism from infectious illness declined by 80%. No
adverse reactions were noted.
Everything that contributes to good health (organic food, sunlight,
pure water, nutrients) helps the immune system. Adverse life styles with
inadequate diet, air pollution, contaminated water and high stress levels
all contribute to slow or incomplete recovery from illness.
What Patients Can Be Helped By Del Immune V (DIV)?
There are many patients who can be helped by DIV. Among these are patients
with:
- Malignant Diseases (cancer, lymphoma, leukemia)
All patients with malignancies have impaired immune function. In a Russian
study 15% of Chernobyl radiation injured patients with cancer, who were
treated with only lactobacillus bulgarica survived. Many others were
able to complete recommended chemotherapy and radiation programs without
bone marrow suppression while taking lactobacillus bulgaricus.
- Autoimmune Diseases All patients with autoimmune
illnesses (systemic lupus erythematosus, multiple sclerosis, auto immune
hepatitis, rheumatoid arthritis, Type 1 Diabetes Mellitus, psoriasis,
the noninfectious form of Addison's Disease, Sjogren's Disease, Hashimoto's
Thyroiditis) have abnormal immune function. DIV can correct the overactivity
of the immune system seen in these patients and promote the return of
normal immune responses.
- Patients With Frequently Recurring and Non-resolving
Infectious Illnesses These patients have a good chance of being
helped with DIV. Included in this category would be sinusitis, bronchitis,
pharyngitis, colds, otitis media, pneumonia, cystic fibrosis, tuberculosis,
hepatitis A,B, and C, malaria, bronchiectasis, urinary tract infections
and osteomyelitis. Recovery in many of these patients could be at least
partially due to a stronger better performing immune system after administration
of DIM. Bacterial resistance does not develop because DIV works on the
immune system and has no effect on infectious organisms.
- Radiation Injury Patients suffering radiation
injury can experience prompt improvement in their suppressed bone marrow
cell production with DIM therapy.
- Patients With Systemic and Chronic Skin Fungal Infections
(cocidiomycosis, histoplasmosis, blastomycosis, cryptococcosis,
sporotrichosis, candidiasis, aspergillosis and mucormycosis). Some of
these patients are known to have specific immune defects such as HIV.
Conventional fungal therapy is not always effective and has toxic side
effects in some patients. Often fungal skin infections resolve with
specific antifungal drug therapy only to recur when the therapy is stopped.
DIV should increase the incidence of complete uneventful recovery by
improving immune function.
- Allergic Diseases Individuals with asthma,
hay fever, urticaria, anaphylaxis, glomerulonephritis, and alveolitis
might notice decreasing symptoms because of a healthier immune system
after use of DIV.
- Diseases With Severe Fatigue One of the most
consistent results of Del Immune V therapy has been relief from severe
fatigue. This means that patients with Chronic Fatigue Syndrome, Fibromyalgia,
Hepatitis and Malignancies are likely to notice significant improvement
in fatigue and energy levels after DIV therapy.
- Gastrointestinal Conditions Probiotic therapy
has been found to be quite helpful in resolving gastrointestinal symptoms
(cramping pain, gas, heartburn, belching, diarrhea, constipation). Prolonged
probiotic therapy has resulted in healing at least one person with severe
ulcerative colitis. There is every reason to believe that Del Immune
V would be at least as effective and possibly exceed probiotic results
for abdominal complaints.
- HIV Infection Patients with AIDS, ARC and
HIV+ who take Del Immune V may have very slow initial improvement in
T4 counts. The T8 values often rise faster than T4. However, clinical
improvement starts at once with decreased infections. Eventually the
T4 count increases and the T4/T8 ratio becomes normal. This improvement
requires 4 to 6 times the usual dose (8 to 12 capsules daily).
- Non-healing Bone Fractures Bone fractures
that do not heal constitute a difficult problem for orthopedic surgeons.
Use of DIV is reported to result in healing of the separated bone fragments.
This may occur because improved immune function allows resolution of
the fibrous tissue separating the bone fragments.
Massive Trauma, Severe Burns And Hospital Acquired Infections
Hospitals are using large amounts of antibiotics. This results in creation
of bacterial species that are resistant to most antibiotics. Unfortunate
patients acquiring these resistant infections may not recover because
of lack of effective pharmaceutical therapy and hospital formularies that
do not contain natural anti-infective healing products.
Patients who suffer major trauma with multiple fractures, lacerations
of liver or spleen and perforated intestines etc. frequently die of serious
infections. These persons have such serious nutritional needs their immune
systems often are unable to construct the immune substances needed to
prevent an overwhelming infections.
Patients with large burns lose massive quantities of protein from the
surfaces where skin has been denuded. There is simultaneous need for the
formation of new skin and subcutaneous tissues. These massive nutritional
needs make it difficult for the immune system to stay healthy and create
enough immune cells and protective substances. This lack often permits
a fatal infection to develop.
Del Immune V begins to work within 6 hours. Patients with severe burns,
massive trauma and hospital acquired infections might be better able to
survive if they were started on Del Immune V before serious infectious
problems have a chance to get started. Most US hospitals do not stock
alternative therapies for infection. For this reason relatives or friends
will need to supply DIV. These critically ill patients need 3 to 4 capsules
of Del Immune V twice daily. In my opinion some of these patients at risk
for life threatening infections may be able to avoid these infections
and have a better chance for survival if they start taking DIV at once
on entry. There is also a real possibility that hospital stays will be
shorter with DIV preventing problems. Obviously some person will need
to know about this immune enhancing therapy and be able to provide it
as most hospitals are solely involved with pharmaceutical products.
Del Immune V Therapy In Hepatitis C
Hepatitis C is a serious illness which often terminates fatally. The
most frequent disease needing liver transplantation is Hepatitis C. Many
persons with Hepatitis C are troubled by "brain fog". These
persons have difficulty carrying out complex mental tasks. They are often
unable to continue in the management type position they held prior to
the onset of Hepatitis C symptoms. Some persons with Hepatitis C have
disabling muscle pain. The course of Hepatitis C is often slowly progressive
until liver transplantation or death occurs.
Approximately 50 patients with Hepatitis C have been treated with DIV.
About half of these patients had disappearance of viral loads, return
of blood tests to normal brain fog ceases and all symptoms disappear.
The remaining half lose their brain fog and feel better. However, they
continue to have abnormal liver function and persisting viral loads in
the blood.
Persons with Hepatitis C should be treated with 2 to 3 capsules of DIV
twice daily. When symptoms and lab studies are normal the DIV can be stopped
but regular health surveillance should be continued.
Case Reports
Case 1 A 47 year old woman developed abdominal fluid
with an enlargement of her girth. Ultrasound disclosed a 10 cm. ovarian
mass. She was started on DIV 2 capsules twice daily for 4 weeks prior
to abdominal surgery. The surgeon was pleasantly surprised in the operating
room because he was able to peel the tumor mass away from the intestine
so no bowel resection was needed. The pathologic specimen showed evidence
of tumor spread (metastasis). This patient has continued DIV 2 capsules
twice daily. Two years later she appears well and her Ca 125 blood test
for ovarian cancer has returned to normal.
Case 2 A 19 year old male with Cystic Fibrosis started
DIV to improve his immune system in a dosage of one capsule twice daily.
He began the DIV during a period when he was ill with a lung infection
severe enough he was contemplating return to the hospital. His symptoms
completely cleared and he was able to gain 9 pounds. Weight gain is normally
quite difficult for cystic fibrosis patients. His FEV-1 breathing test
has improved from 28 % to 37 %. He states that "he is unable to recall,
when he has felt this good". His family is convinced that he is better
than he has been for several years.
Case 3 A female with long standing yeast problems had
failed to exhibit significant improvement despite Crook low yeast low
sugar diet and Nystatin. She was bothered by a heavy vaginal discharge,
urinary frequency and urgency, severe abdominal cramping whenever she
ate carbohydrates such as sugar, processed foods, beer and wine. On this
dietary program for 6 months her symptoms were less but still present.
She started on DIV one capsule twice daily but lowered her dose to one
daily after 3 days. Within 48 hours her symptoms were gone, sleep was
improved, energy was better, and her health has remained fine with no
vaginal discharge or cramping pain. She continues on a carbohydrate restricted
diet and DIV.
Case 4 This 60 year old male had a transurethral resection
of the prostate followed in six weeks by a radical prostatectomy for cancer.
He was weak, had frequent colds and had a chronic fungal infection of
his feet and ankles. To improve his immune system he began DIV. Within
three days his energy level was higher than it had been in years In 10
days the fungal foot infection was gone and did not return. His chronic
daily episodes of severe heartburn, diarrhea and cramping pain were greatly
improved and have remained so. He remains on DIV.
I think Del Immune V represents an important advance in health care
because it has the ability to significantly improve immune system function.
This product avoids the inconsistent performance seen with the living
bacteria probiotic substances.
Footnotes:
1, Wilson, James ND, PhD. The Immunity System pg. 4 Nutrition Dynamics
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