Magnesium and Radiation Protection
by
Dr. Mark Sircus
It is in a list of medicinals that prevent and treat
cancer that we find helpful substances that treat
and strengthen us against radiation contamination.
"In the years leading up to Chernobyl, some dairy farmers in Austria
were using remineralization as a part of their operations. They added
rock dust to liquid manure as well as combining it with compost, thereby
removing odors and greatly increasing soil biota. As a result, cows had
twice the normal lifespan and produced much more milk. Amazingly enough,
after Chernobyl, the cheeses that were remineralized (as well as biodynamic
cheeses) measured no radioactivity whatsoever. Austrians would stand in
long lines in order to buy these safe, remineralized products" writes
Joanna
Campe.
Iodine is obviously not the only substance that we should run to in
the face of increasing radiation threats. Magnesium is a vital
mineral whose lack leaves us open to not only radioactive damages but
also those from heavy metals and thousands of chemicals, which
we are commonly exposed to. Mercury and now a long list of radioactive
particles are floating in the environment like invisible clouds that have
spread out everywhere. They are raining down on us, damaging and damning
our future. We can no longer be passive about building our defenses against
the toxic onslaught.
Without sufficient magnesium, the body
accumulates toxins and acid residues,
degenerates rapidly, and ages prematurely.
Just about everyone who is writing protocols for radiation toxicity
is forgetting about the importance of magnesium salts. Worse still are
governments and the entire institution of medicine that are purposely
ignorant about magnesium, so they cannot possibly be trusted for valuable
health and medical information that will help us in our time of dire need.
The need was dire before Fukushima but they did not want to admit that;
they let the public get obsessed with CO2 emissions and said nothing about
the mercury. Now with radioactive nuclides steadily building up in the
background, we are in trouble than any of us care to admit. Today the
situation has gone nuclear and there has never before been a need so great
for detoxification and chelation.
Magnesium is a crucial factor in the natural self-cleansing
and detoxification responses of the body. Magnesium is also necessary
for effective chelation. It stimulates the sodium potassium pump on the
cell wall and this initiates the cleansing process in part because the
sodium-potassium-ATPase pump regulates intracellular and extracellular
potassium levels. The healthy cell wall favors intake of nutrients and
elimination of waste products.
The involvement of free radicals in tissue injury induced by magnesium
deficiency [1] causes an accumulation of oxidative products in heart,
liver, kidney, skeletal muscle tissues and in red blood cells, [2] leaving
them more vulnerable to oxidative stress caused by radiation exposure.
Both radiation exposure and heavy metals produce oxidative stress through
the creation of increased levels of reactive oxygen species (ROS-oxygen
free radicals, peroxides, and singlet oxygen). It is known that these
increased levels of intracellular ROS are sufficient to trigger apoptosis
(cell death).
Glutathione is Magnesium-Dependent
Glutathione protects the cells from oxidative-stress-induced apoptosis
and glutathione levels are magnesium dependent! "Glutathione is
a very important detoxifying agent, enabling the body to get rid of undesirable
toxins and pollutants. It forms a soluble compound with the toxin that
can then be excreted through the urine or the gut. The liver and kidneys
contain high levels of glutathione as they have the greatest exposure
to toxins. The lungs are also rich in glutathione partly for the same
reason. Many cancer-producing chemicals, heavy metals, drug metabolites
etc. are disposed of in this way," says Dr. Patricia Kongshavn,
former professor, department of medicine at McGill University.
Glutathione is a polypeptide,
C10H17N3O6S, of glycine, cysteine, and glutamic acid.
Glutathione synthetase requires -glutamyl cysteine, glycine,
ATP, and magnesium ions to form glutathione. [3] In magnesium
deficiency, the ss y-glutamyltranspeptidase is lowered. [4]
There is a direct relationship between cellular magnesium, GSH/GSSG ratios,
and tissue glucose metabolism. [5]
Magnesium deficiency causes glutathione loss and this is unwelcome as
the clouds of radiation are touching down across the northern hemisphere.
Magnesium deficiency causes glutathione loss, which is
not at all healthy because glutathione helps to defend the body against
damage from cigarette smoking, exposure to radiation, cancer chemotherapy,
and toxins such as alcohol and just about everything else.
According to Dr. Russell Blaylock, low magnesium is associated
with dramatic increases in free radical generation as well as glutathione
depletion and this is vital since glutathione is one of the few
antioxidant molecules known to neutralize mercury. [6]
"For every molecule of pesticide that your body detoxifies, you
throw away or use up forever a molecule of glutathione, magnesium and
more," says Dr. Sherry Rogers who goes on to say that, "Your
body uses nutrients to make this glutathione and it uses up energy as
well. Every time we detoxify a chemical, we use up, lose, throw away forever,
a certain amount of nutrients."
Mineral Deficiencies
Deficiencies in basic minerals like magnesium and selenium can
make all the difference between health and disease, between being able
to withstand chemical, heavy metal and radiation exposure. Dr.
Rogers has indicated that there is as much as a 500-fold difference in
the ability of individuals to detoxify the same chemicals and much of
that will be true for radiation as well. A key marker of this difference
is each individual's magnesium level. Deficiencies in magnesium
will wreak havoc with our body's ability to detoxify and chelate
heavy radioactive particles and explains much of the difference between
one person withstanding radiation exposures and another person falling
to radiation sickness.
Dr. Leslie Fisher has treated in excess of 35,000 patients where mineral
therapy was prescribed as the sole form of medication. He has conducted
research within his own clinics and the Department of Psychiatry, Austin
Hospital, Melbourne. Mineral therapy is the foundation upon which chelation [7]
treatments and protocols are built. Magnesium does protect cells from
aluminum, mercury, lead, cadmium, beryllium and nickel, which explains
why re-mineralization is so essential for heavy metal detoxification and
chelation as well as radiation protection. Magnesium is essential for
the survival of our cells but takes on further importance now where our
bodies are being bombarded on a daily basis with heavy metals and radiation.
Radiation and Diabetes
No one is going to convince the public that the increasing radiation
will have a general effect on our health that can be easily traced back
to the source. Even before we get cancer from radiation we have a general
down-spiraling of body functions because of all the oxidative stress.
In my book, New Paradigms in Diabetes, I write extensively about
the direct relationship between magnesium deficiency and the onset of
diabetes.
Pancreatic beta cells are sensitive to reactive oxygen species
(ROS) [8]
attack when they are exposed to oxidative stress, [9]
because of the relatively low expression of antioxidant enzymes such as
catalase and glutathione peroxidase. [10]
Diabetes is typically accompanied by increased production of free radicals
and/or impaired antioxidant defense capabilities, indicating a central
contribution of reactive oxygen species. It is also a fact that ROS is
one of the major factors that induce oxidative modification of DNA and
gene mutation. [11]
The Chernobyl incident was a major disaster of humanity, which has resulted
in a plethora of health problems that are still far from being fully recognized.
Most studies analyzing the medical consequences of this catastrophe have
so far focused on diseases such as thyroid cancer, leukemia, immune and
autoimmune pathology [12] [13] even though an increase in the incidence of type 1 diabetes mellitus,
a disorder involving the immune system, was observed within the residential
population of Hiroshima among survivors of the atom bomb detonation. [14]
Studies have also shown that thymectomy and a sub-lethal dose of gamma
radiation induces type 1 diabetes in rats. [15]
Researchers at the Pediatric Hospital A. Meyer, Florence, Italy studied
this question by assessing the incidence of the disease in children in
Gomel, Belarus in the years subsequent to the Chernobyl disaster. The
results of the study seem to confirm the hypothesis that environmental
pollution such as that subsequent to the Chernobyl accident can cause
diabetes. [16]
Mass screening for diabetes mellitus has been conducted on 64,000-113,000
atomic bomb survivors residing in Hiroshima City since 1961. From
1971 to 1992 a 2.7-fold increase in the prevalence of diabetes mellitus
was observed in males and a 3.2-fold increase in females. [17]
We have a significant and documented increase in
the incidence of type 1 diabetes in children and
adolescents after Chernobyl in the radioactively
contaminated area of Gomel compared to Minsk.
Heinrich Heine University
When beginning to build a protocol against the radiation and heavy metal
onslaught, we need to stick with the basics and they are magnesium, iodine,
sodium bicarbonate, vitamin C, selenium, clay, THC (cannabis), as well
as a natural chelator and superfoods. Properly filtered water also is
essential. There is always more we can do but even affording these basics
is a challenge to many.
Special Note: One of my readers wrote saying, "Thank
you for the labor of love you've given to the inhabitants of the
world. All the information about magnesium, iodine, baking soda, etc.
is priceless and very much appreciated. I know we can't thank you
enough for your generosity with the knowledge you've accumulated
from all of your research. I know you've had your detractors–ignore
them!" These basic medicines are not only the mainstay of emergency
rooms and intensive care wards but are the backbone of a my new form of
medicine called Natural Allopathic Medicine, which makes sense in the
age of toxicity that we all have live in.
References
[1] Magnesium deficiency (MgD) has been associated with production
of reactive oxygen species, cytokines, and eicosanoids, as well as vascular
compromise in vivo. Although MgD-induced inflammatory change occurs
during "chronic" MgD in vivo, acute MgD may also affect the
vasculature and consequently, predispose endothelial cells (EC) to perturbations
associated with chronic MgD. As oxyradical production is a significant
component of chronic MgD, we examined the effect of acute MgD on EC
oxidant production in vitro. In addition we determined EC; pH, mitochondrial
function, lysosomal integrity and general cellular antioxidant capacity.
Decreasing Mg2+ (< or = 250microM) significantly increased EC oxidant
production relative to control Mg2+ (1000 microM). MgD-induced oxidant
production, occurring within 30 min, was attenuated by EC treatment
with oxyradical scavengers and inhibitors of eicosanoid biosynthesis.
Coincident with increased oxidant production were reductions in intracellular
glutathione (GSH) and corresponding EC alkalinization. These data suggest
that acute MgD is sufficient for induction of EC oxidant production,
the extent of which may determine, at least in part, the extent of EC
dysfunction/injury associated with chronic MgD. Effect of acute magnesium
deficiency (MgD) on aortic endothelial cell (EC) oxidant production.
Wiles ME, Wagner TL, Weglicki WB.The George Washington University Medical
Center, Division of Experimental Medicine, Washington, D.C., USA.
mwiles@nexstar.com Life Sci. 1997;60(3):221-36.
[2]
Martin, Hélène. Richert, Lysiane. Berthelot, Alain Magnesium
Deficiency Induces Apoptosis in Primary Cultures of Rat Hepatocytes.*
Laboratoire de Physiologie, etLaboratoire de BiologieCellulaire, UFR
des Sciences Médicales et Pharmaceutiques, Besançon,
France. 2003 The American Society for Nutritional Sciences J. Nutr.
133:2505-2511, August 2003.
[3] Virginia Minnich, M. B. Smith, M. J. Brauner, and Philip W. Majerus.Glutathione
biosynthesis in human erythrocytes. Department of Internal Medicine,
Washington University School of Medicine, J Clin Invest. 1971 March;
50(3): 507–513. Abstract: The two enzymes required for de novo
glutathione synthesis, glutamyl cysteine synthetase and glutathione
synthetase, have been demonstrated in hemolysates of human erythrocytes.
Glutamyl cysteine synthetase requires glutamic acid, cysteine, adenosine
triphosphate (ATP), and magnesium ions to form ?-glutamyl cysteine.
The activity of this enzyme in hemolysates from 25 normal subjects was
0.43±0.04 ?moleglutamyl cysteine formed per g hemoglobin per
min. Glutathione synthetase requires ?-glutamyl cysteine, glycine, ATP,
and magnesium ions to form glutathione. The activity of this enzyme
in hemolysates from 25 normal subjects was 0.19±0.03 ?mole glutathione
formed per g hemoglobin per min. Glutathione synthetase also catalyzes
an exchange reaction between glycine and glutathione, but this reaction
is not significant under the conditions used for assay of hemolysates.
The capacity for erythrocytes to synthesize glutathione exceeds the
rate of glutathione turnover by 150-fold, indicating that there is considerable
reserve capacity for glutathione synthesis. A patient with erythrocyte
glutathione synthetase deficiency has been described. The inability
of patients' extracts to synthesize glutathione is corrected by
the addition of pure glutathione synthetase, indicating that there is
no inhibitor in the patients' erythrocytes.
[4] Braverman,
E.R. (with Pfeiffer, C.C.)(1987). The healing nutrients within: Facts,
findings and new research on amino acids. New Canaan: Keats Publishing.
[5] Barbagallo, M. et al. Effects of glutathione on red blood cell intracellular
magnesium: relation to glucose metabolism. Hypertension. 1999 Jul;34(1):76-82.
Institute of Internal Medicine and Geriatrics, University of Palermo,
Italy.mabar@unipa.it
[6] http://www.dorway.org/blayautism.txt
[7] Chelation is a recognized treatment for heavy metal poisoning (such
as lead and mercury)
[8] ROS (Reactive Oxygen Species) are natural byproducts of oxygen metabolism
in the body. Free radicals and other byproducts are formed as a result
of this metabolism, and at lower levels can be very beneficial, but
when too many of these byproducts are formed the situation of oxidative
stress occurs. Reactive oxygen species (ROS) include oxygen ions,
free radicals and peroxides both inorganic and organic. They are generally
very small molecules and are highly reactive due to the presence of
unpaired valence shell electrons. Oxidative stress is a medical term
for damage to animal or plant cells (and thereby the organs and tissues
composed of those cells) caused by excesses of these reactive oxygen
species, which include (but are not limited to) superoxide, singlet
oxygen, peroxynitrite or hydrogen peroxide. Superoxide is produced
deleteriously by 1-electron transfers in the mitochondrial electron
transfer chain. It is defined as an imbalance between pro-oxidants
and anti-oxidants, with the former prevailing. The causes of these
excesses are many, and include environmental influences of every type.
Enzyme activities are sometimes affected negatively, leading to greater
production of excess ROS, and heavy metals such as chromium, vanadium,
and others are said to be involved, now this new evidence that methylmercury
definitely plays a significant role in the pancreas. Cells are normally
able to defend themselves against ROS damage through the use of enzymes
such as superoxide dismutases and catalases. Small molecule antioxidants
such as Ascorbic acid (vitamin-C), uric acid, and glutathione also
play important roles as cellular antioxidants. Similarly, Polyphenol
antioxidants assist in preventing ROS damage by scavenging free radicals.
Studies are conflicting on some antioxidants such as Vit. E. The resulting
inflammatory processes are believed to be the result of these ROS
excesses and include cardiovascular disease, ALS, neurodegenerative
diseases, and many others.
[9] Kajimoto, Y., and Kaneto, H. (2004) Role of oxidative stress in pancreatic
beta-cell dysfunction. Ann. N. Y. Acad. Sci. 1011, 168-176.
[10] Tiedge, M., Lortz, S., Drinkgern, J., and Lenzen, S. (1997) Relation
between antioxidant enzyme gene expression and antioxidative defense
status of insulin-producing cells. Diabetes 46, 1733-1742.
[11] Inoue, M., Sato, E. F., Nishikawa, M., Hiramoto, K., Kashiwagi,
A., and Utsumi, K. (2004) Free radical theory of apoptosis and metamorphosis.Redox
Rep. 9, 237-247.
[12] Kuzmenok O, Potapnev M, Potapova S et al. (2003) Late effects of the
Chernobyl radiation accident on T cell-mediated immunity in cleanup
workers. Radiat Res 159: 109–116.
[13] Lomat L, Galburt G, Quastel MR, Polyakov S, Okeanov A, Rozin S
(1997) Incidence of childhood disease in Belarus associated with the
Chernobyl accident. Environ Health Perspect [Suppl 105] 6:1529–1532.
[14] Ito C (1994) Trends in the prevalence of diabetes mellitus among
Hiroshima atomic bombsurvivors. Diabetes Res ClinPract [Suppl]:S29–S35.
[15] Ramanathan S, Bihoreau MT, Paterson AD, Marandi L, Gauguier D,
Poussier P (2002) Thymectomy and radiationinduced type 1 diabetes
in nonlymphopenic BB rats. Diabetes 51:2975–2981.
[16] J PediatrEndocrinolMetab. 2002 Jan;15(1):53-7. Incidence of childhood
type 1 diabetes mellitus in Gomel, Belarus.Martinucci ME, Curradi
G, Fasulo A, Medici A, Toni S, Osovik G, Lapistkaya E, Sherbitskaya
E. Regional Centre for Juvenile Diabetes, Paediatric Hospital A. Meyer,
Florence, Italy.
[17] Trends in the prevalence of diabetes mellitus among Hiroshima atomic
bomb survivors. Diabetes Res ClinPract. 1994 Oct;24 Suppl:S29-35.
Hiroshima Atomic Bomb Casualty Council, Health Management Center,
Japan.
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