Coenzyme Q10

Coenzyme Q10 (or CoQ10 for short) is also known as ubiquinone or ubiquinol.  CoQ10 helps aid in the body’s energy production by assisting the mitochondria in producing ATP.  It is a vitamin-like nutrient that is fat-soluble and has powerful antioxidant activity that can even recharge the activity of other antioxidants.

Supplementing with CoQ10 helps your cells to breathe (cellular respiration) and produce more energy.  It improves the function of your mitochondria.  Mitochondria that aren’t functioning well can cause a host of problems.

Why Do We Need It?

CoQ10 production in the body declines as people reach their 30’s.  When the levels of Coenzyme Q10 start dropping, so does our health.  Once levels drop to a certain point we can start to see cardiovascular issues begin.  Other health issues are weak immunity, periodontal problems, lack of energy and weight gain.

Some viral infections can cause damage to your mitochondria. In that case supplementing with CoQ10 to help the function of your mitochondria is very important.

Fibromyalgia sufferers often have CoQ10 levels that are unevenly distributed in the body.  This can cause increased oxidative stress and can contribute to chronic pain and inflammation.

Deficiencies

Deficiency of CoQ10 can manifest in many ways including high blood pressure, hair loss, liver disease, damaged cell membranes, heart attacks, congestive heart failure, exhaustion, migraines, gum disease and more.

ACE Inhibitors, calcium channel blockers, beta blockers and blood pressure medications deplete CoQ10 in the body.

A deficiency of CoQ10 can also affect your brain, muscles and your kidneys.  Brain effects can include problems with coordination and seizures.

Deficiencies can also cause weakened muscles or muscle stiffness, vision loss caused by degeneration of the optic nerve or issues with the retina.  It can also cause impaired kidney function, reduction of red blood cells and certain white blood cells, cause abnormal blood clotting and even kidney failure.

Benefits Of Taking CoQ10

  • May help with preventing certain types of migraines
  • Can prevent oxidation of LDL cholesterol in the body
  • Protects the heart from lack of oxygen
  • Can help with fatigue
  • Parkinson’s Disease
  • Congestive Heart Disease
  • Cardiovascular Disease
  • Stroke
  • Can help lower insulin resistance when combined with proper diet

CoQ10 and Cholesterol

When CoQ10 is depleted in the body, it causes LDL cholesterol to become oxidized.  This starts a chain-reaction of events and makes the LDL bore holes in your arterial walls which causes inflammation.  This will increase your chances of a heart attack or stroke when this happens.

Statin use inhibits the production of cholesterol and CoQ10.   If you are on a statin medication, you probably need to be taking CoQ10. If you are on these medications, consider discussing supplementation with your healthcare provider.

Many people are still under the impression that a low-fat diet is the way to prevent heart disease.  This notion is completely false and yet encouraged by the big food companies that want to sell you their processed low-fat, high sugar foods.  CoQ10 is fat soluble so you are further sabotaging your health by not eating healthy fats so your body can absorb CoQ10.  Healthy fats are extremely important for our bodies.

Dosage And Cautions

How much do you need to take?  1 mg per pound of body weight is recommended for normal use.

In clinical trials, Parkinson’s patients saw improvement in dosages of 1200mg per day (in divided dosages throughout the day).  They tested lower and higher dosages and 1200mg was the most effective dosage (so more isn’t always better!)

A study published in the Journal Of Clinical Psychopharmacology found that 18 people with depression who took 400-800mg per day for a month decreased the severity of depression and improved symptoms of fatigue, sadness, brain fog and difficulty concentrating.  If you are on medication for depression, please discuss this option with your healthcare provider.

Caution is advised if you are taking blood thinning medications such as Warfarin.  Consult your healthcare provider.

 

 

 

Further Reading And References:

Who Should Consider Coenzyme Q10?

https://www.life-enthusiast.com/articles/coenzyme-q-10-for-heart-and-immunity/

https://www.functionalmedicineuniversity.com/public/883.cfm

Is CoQ10 Right For You? Here’s How To Know

https://medlineplus.gov/genetics/condition/primary-coenzyme-q10-deficiency/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150987/

Author: Alicia Passmore