Here is a brief history of the development of Aloe Vera concentrates or muco-poly-saccharides, and the products that came and went.
Acemannan is a term that defines the molecular weight range of mucopolysaccharides derived from Aloe Vera gel that are over 1,000,000 Daltons. All of the mucopolysaccharides from Aloe Vera gel below this molecular weight are not considered to be Acemannan. Carrington Labs was the single company that had the right to the name Acemannan, with patented extraction processes used to produce Acemannan as well as powdered Aloe Vera gel products that contained mucopolysaccharides that were less than 1,000,000 Daltons. The non-Acemannan mucopolysaccharide extract in a powder form was known as Manapol.
From a more technical point of view, Acemannan can be defined as a D-isomer mucopolysaccharide that is extracted from aloe leaves. Acemannan has been demonstrated to induce macrophages to secrete interferon, tumor necrosis factor-a, and interleukins - which might help in preventing or abrogating viral infection. These three cytokines are known to cause inflammation and interferon is released in response to viral infections. In vitro studies have shown to inhibit HIV replication. Acemannan is currently being used for treatment and clinical management of fibrosarcoma in dogs and cats. Administration of acemannan has been shown to increase tumor necrosis or prolonged survival and the animals have demonstrated lymphoid infiltration and encapsulation.
While Carrington Labs was still operational before going out of business in 1999, the name acemannan was highly protected by this company. Health Breakthroughs International had a close working relationship with Carrington Labs over ten years ago, but went its own way with an Aloe Vera gel powder extract that is actually much higher than any product that was sold by Carrington Labs in regards to Acemannan. MPS contains long unbranched polysaccharides consisting of a repeating disaccharide unit. The repeating unit consists of a hexose (six-carbon sugar) or a hexuronic acid, linked to a hexosamine (six-carbon sugar containing nitrogen). MPS Gold is a product name Health Breakthroughs International created in 1995 to represent the fact that it contains mucopolysaccharides in a broad range of molecular weights of this molecule.
In fact, MPS Gold contains 20% Acemannan, with a range in molecular weight from 1,000,000 Daltons up to 5,000,000 Daltons. No other Aloe Vera gel or glycountrient product contains a higher concentration of Acemannan than MPS Gold. In fact, Health Breakthroughs International is one of the few producers of Aloe Vera and glyconutrient products that provide a published molecular weight assay to prove the Acemannan content. Click Here to review molecular weight information about MPS Gold.
MPS Gold is absolutely the best product available when it comes to Acemannan content and is actually better than what was available from Carrington Labs in the form of Manapol. What most people didn't realize is that Manapol contained almost zero Acemannan. Acemannan was only used for Carrington Labs pharmaceutical products (not available to the general public or doctors, but only to hospitals for wound care and to veterinarians to treat dogs and cats for specific types of cancer and leukemia). Where as Manapol contain less than the complete range of molecular weights of mucopolysaccharides, MPS Gold contains the complete range of molecular weights. Having a complete product is very important because Acemannan has the upper molecular weight range mucopolysaccharides that are responsible for powerful immune system responses that are not associated with the lower molecular weight ranges.
Acemannan and the other molecular weight ranges of the mucopolysaccharides found in MPS Gold are the only essential glyconutrient sugars required by the cells. Again, as we have pointed out throughout our website, the other eight, ten, or whatever number of other plant extract sugars other companies come up with to use in various product formulas are not essential or even necessary. The more the MPS molecules are diluted in terms of the other product formulas available, the more a person will lose the complete healing power of the only two essential glyconutrients found in Acemannan and in the total molecular weight range, which are mannose and galactose.