My niece, who suffers from severe level SLE and Fibromyalgia, has been using aminos for almost two years and I believe it has brought her ANA titer down considerably and contributed to a reduction in the severity of her symptoms. After a short period during which she ceased taking the product, her condition worsened. Once we had her back on the regime, the improvements returned also. This gives us sufficient reason to stay on it, as mainstream medications - of which we have tried most - simply are not effective, and most carry toxic side effects. My advice - try this, it just might do the job for you as well.