I had no pain all day almost immediately upon usage. I was traveling a few days ago and it was the one supplement I took on the plane. Well, I think it fell out of my purse because I have not located it. After writing this review, I plan to order a new bottle with hopes it reaches me in a
few days. It has been true to the description and the reviews of others. Got to go place my order. You too will probably write a review of complete satisfaction. I am grateful for Arthritis Ease.