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Rutin

Rutin is a member of bioflavonoids, a large group of phenolic secondary metabolites of plants that include more than 2,000 different known chemicals. Bioflavonoids such as Quercetin, Rutin, and Hesperidin are important nutrients due to their ability to strengthen and modulate the permeability of the walls of the blood vessels including capillaries. Rutin is known to offer nutritional support to the circulatory systems including the capillaries in eyes. It has proved to be especially helpful in preventing recurrent bleeding caused by weakened blood vessels, and has been used in treatment of hemorrhoids and varicose veins, helping to prevent blood vessel walls to become fragile. Rutin is safe and effective for: Poor Circulation, High Blood Pressure, Varicose Veins, Chilblains, Capillary Fragility, etc.

Rutin is found in buckwheat grains and plants (but not in other grains). Buckwheat has been cultivated for at least 2,000 years, starting in China, and consumed in China, Korea and Japan for more than thousand years, in the form of buckwheat jelly and buckwheat noodle (soba). Buckwheat has recently been found to be effective in reducing high blood pressure and slowing the aging process. Buckwheat is rich in proteins (12-15%) and essential amino acids such as lysine (5-7%) that are deficient in major cereal crops, and is also abundant in lipids, minerals (iron, phosphorus, and copper), and vitamins (B1 and B2) and rutin. Rutin is found in buckwheat grains and plants (but not in other grains). Buckwheat has become a highly safe and healthy medicinal plant with efficacies for vascular disorders caused by fragile or permeable capillaries.

Buckwheat flowers are important honey source in Korea and other Asian countries. Rutin is not found in other grains such as rice, wheat, etc. or beans, but is contained in great quantity (4-6%) in buckwheat. Rutin strengthens capillaries, helping people recover from arteriosclerosis (the hardening of the arteries) or high blood pressure. Rutin belongs to a group of plant compounds called bioflavonoids that also include the important catechins of green tea and the polyphenols of red wine. Recent studies have shown that the bioflavonoids are powerful antioxidants that fight free radicals. Free radicals are said to be responsible for as much as 90 percent of all the human diseases, such as cancer, arteriosclerosis, strokes, senility due to aging, etc.

Research About Rutin!

Historically, buckwheat has been a food crop, and recently it is increasingly receiving attention as an important medicinal herb due to the discovery of health benefits of buckwheat and its main constituent, rutin.

Research reports citing rutin and buckwheat are provided:

Crit Rev Food Sci Nutr 1983;19(3):213-58 - Buckwheat: structure, composition, and utilization

Eur J Clin Pharmacol 1996;50(6):443-7 - Leg oedema protection from a buckwheat herb tea in patients with chronic venous insufficiency: a single-centre, randomised, double-blind, placebo-controlled clinical trial

J Agric Food Chem 1999 Oct;47(10):4384-7 - Effect of processing on the flavonoid content in buckwheat (Fagopyrum esculentum Moench) grain

J Clin Pharmacol 2001 May;41(5):492-9 - Pharmacokinetics and bioavailability of quercetin glycosides in humans

Int J Cancer 2002 Apr 10;98(5):761-9 - Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosis

Biochem Pharmacol 2001 Mar 15;61(6):677-84 - Enhancement of antioxidant and anti-inflammatory activities of bioflavonoid rutin by complexation with transition metals

J Bone Miner Res 2000 Nov;15(11):2251-8 - Rutin inhibits ovariectomy-induced osteopenia in rats

Cell Biol Toxicol 2000;16(2):91-8 - Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors

J Ethnopharmacol 2000 Jul;71(1-2):45-53 - Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions

FEBS Lett 2000 May 12;473(2):145-8 - Flavonoids can replace alpha-tocopherol as an antioxidant

Carcinogenesis 2000 May;21(5):921-7 - Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis

BMJ 2002;324:689-690 ( 23 March ) - New treatments for varicose veins

Journal of Health Science - Effects of Rutin on Serum and Hepatic Lipid Levels

Farmaco 2001 Sep;56(9):683-7 - Anti-inflammatory properties of plant flavonoids. Effects of rutin, quercetin and hesperidin on adjuvant arthritis in rat

Biochem Pharmacol 2001 Sep 15;62(6):743-6 - Oxidative stress in rheumatoid arthritis leukocytes: suppression by rutin and other antioxidants and chelators

Minerva Cardioangiol 2001 Apr;49(2):159-63 - Effectiveness of the combination of alpha tocopherol, rutin, melilotus, and centella asiatica in the treatment of patients with chronic venous insufficiency

USDA medicinal plant database, Dr. James A. Duke

A Modern Herbal homepage - Herbal and Botanical Archive

Herbs.org - Herb World News Online: Top News


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