Glutamine: Amino Acid for Body Repairs

Glutamine is the most abundant amino acid in your body.

During times of stress (exercise, trauma/shock, illness) your body’s demand can outweigh supply. As a result, blood Glutamine levels have been shown to drop by over 50%.

It’s classified as an essential amino acid. This means your body does not make it. You must supplement it.

An amazing variety of body functions depend on and are improved by abundant supply of glutamine.

Key To Body Repairs

  • Immunity
  • Digestion
  • Muscle Repair
  • Brain Functions
  • pH Balance

Glutamine users often report more energy, less fatigue and better mood.


Glutamine supports the natural synthesis of one key antioxidant and immune-boosting chemical, glutathione. Provides general disease-fighting insurance.


Glutamine helps prevent pathogens from permeating your intestinal wall. It’s the primary material for regenerating your intestinal lining. When the lining is healthy, nutrients pass into your bloodstream. Prevents toxins from entering your system.

It’s used as and energy source by all rapidly dividing cells. Especially cells of your intestinal lining. And certain immune cells (thymocytes, lymphocytes and macrophages). Without sufficient Glutamine, your intestines cannot maintain health. Then immune function breaks down.

If you’re low in glutamine and have serious a digestive condition, then skeletal muscle tissue is used. This creates a cascade of problems, including slower metabolism and an increased tendency to store body fat.

Muscle Repair

Glutamine is the most abundant freeform protein in muscle. Comprises about 50% of the amino acid structures. An important muscle-building amino acid. By far the most important amino acid for body builders.

Helps replenish muscle glycogen after exercise. Without sufficient glutamine, muscles begin to atrophy.

As tissue is stressed and damaged (physical or emotional), higher levels of glutamine are required for repair.

There are two principal functions of glutamine in muscle tissue:

  1. Protects muscle tissue from cortisol – a hormone released from exertion or stress. Cortisol attaches itself to muscle cell receptor sites and consumes the tissue. Glutamine acts as a protective barrier for the muscle tissue.
  2. Supports the natural release of human growth hormone. This supports skeletal muscle repair and overall cellular recovery. Excellent to reduces signs of aging.

Brain Function

Glutamine is an abundant protein in the fluid surrounding your brain and spine (cerebrospinal fluid). Supplemental Glutamine is brain food and an energy booster.

Studies show that glutamine functions as an antidepressant. And can help in addiction recovery.

It’s an important precursor to key neurotransmitters. They send impulses  from your brain to nervous system tissues. Glutamine is also an important energy source for your nervous system. If your brain doesn’t get enough glucose, it compensates by increasing glutamine metabolism for energy.

In your brain, Glutamine helps produce both excitatory and inhibitory neurotransmitters. Glutamate and GABA (gamma-aminobutyric acid).

Glutamine protects your body, especially your brain from ammonia toxicity.

About Ammonia Toxicity:

  • Enables development of neurodegenerative diseases.
  • Interferes with the oxidative metabolism of neurons. Reduces ATP production (cellular energy).
  • Gives rise to very harmful nitrogen-based free radicals.

pH Balance

If your blood pH too acidic, more Glutamine is directed to your kidneys, correcting acidosis.

If blood pH is too alkaline, more glutamine is sent to your liver, correcting  alkalosis.

And there’s still more…

Glutamine is one amino acids that control the volume of cellular water. And the osmotic pressure (osmoregulation) in various tissues.

Helps control of low blood sugar. Easily converted to glucose when blood sugar is low.

Glutamine regulates the expression of certain genes, including those that govern certain protective enzymes. And helps regulate the biosynthesis of DNA and RNA.

Recently it has been discovered that glutamine is important for the cardiovascular system as well.

Sources of Glutamine

Glutamine-rich foods include fish, meat, dairy, grains, and beans.

Glutamine supplements are usually derived from the protein in whey or wheat.

There are two forms that are generally available-l-glutamine (the freeform amino acid) and glutamine peptides (partially digested).

L-glutamine, although it is the purest form of supplemental glutamine, is less stable to store over time. It should be kept in a cool, dark location.

Glutamine is a protein produced by a conversion process in your liver and skeletal muscles. Your body uses glutamic acid (nonessential amino acid) and adds an additional nitrogen atom.

An ideal time to take Glutamine is before bed.

Scientific References: Amino Acids

Author: Life Enthusiast Staff