HGH is a 191-amino acid protein chain; it's far too large to absorb orally or sublingually, even in a sugar formula (the sugar doesn't absorb sublingually either). Not only that but if it WAS all absorbed you'd need two ounces daily of the most potent formula on the market to get the levels you need to meet the requirement for material IGF-1 increase. That's why the doctors don't send you home with HGH pills; injections are a requirement for exogenous HGH.

Out of more than 100 secretagogue products tested in a clinical setting by blood analysis, the one anti-aging specialists chose to rely on is SomaLife gHP, an amino acid blend. Even blending their own amino acids similarly produced much less HGH, partly because of the lack of purity of amino acids in North America. SomaLife gHP is pharmaceutically pure. Of course dosage and ratio are both important and this is where the concept has been refined over the last 20 years.

Question for Duncan Crow:

There are many who surprisingly actually want low levels of hGH, IGF-1 and testosterone, because of the association with prostate (and other) cancers.

Answer:

Misinformation. There's no association between HGH or IGF-1 and cancers; in fact, in the HGH clinical studies, the subjects did not experience as much cancer as the controls. Moreover, no increase in prostate cancer or any other malignancy was observed in approximately 3,000 patients during long term treatment with recombinant growth hormone.

In his book entitled Grow Young with HGH Dr. Ronald Klatz, president of the American Academy of Antiaging Medicine, reported on the patients treated by Drs. Chein and Terry with human growth hormone injections. Of 800 patients the only side effects that had been reported were minor joint aches and pains and some fluid retention. These symptoms disappeared in the first couple of months.

More significantly was the fact that there were no reported cases of cancer among all 800 patients treated at their clinic. It is very reassuring since some investigators have been concerned that growth hormone would cause undetected cancer cells to divide more rapidly.

Even so, you would think with 800 people over the age of 40-years- old, given the normal incidence of cancer, some of these people would certainly get the disease. It could be that there is some sort of protective effect of growth hormone replacement, probably through the immune system.

Even more compelling in this study was the act that PSA levels as a marker of prostate problems including cancer did not increase among any of the male patients. In one case study, with Chein and Terry, growth hormone actually seemed to have reversed the course of the prostate cancer. The patient came to see Dr. Chein with a PSA level of over 50, normal being 0 to 4 and men with cancer usually having a PSA level in the 10s or 20s. The diagnosis of adenocarcinoma was confirmed by a needle biopsy. Although existing cancer is normally a contraindication for hormone replacement therapy, the patient did refuse surgery and urged Dr. Chein to treat him with growth hormone as well as DHEA, melatonin, but not testosterone. In a short period of time the man's PSA levels came down to between 5 and 7. This is absolutely spectacular as the disease has gone into remission. Dr. Chein speculates that through the immune stimulation of growth hormone, natural killer cells were effectively able to destroy the cancer cells.

Further clinical studies have similarly failed to link elevated GH and IGF-1 levels with cancer. In fact, arginine, a growth hormone increasing amino acid, has proven anti-tumor effects (chemotherapeutic), and it's use also reduces wasting (cachexia) associated with cancer.

Anti-aging guru Leon Cass Terry, M.D., Ph.D., Pharm.D., says, "On the positive side, we have observed many beneficial effects of low dose/high frequency HGH supplementation, as follows: Increased lean body mass; Decreased fat mass; Increased strength and endurance; Increased sexual desire and performance; Increased quality of life; Increased energy and stamina; Increased memory capacity and recall; Decreased fatigue; Increased capacity in aerobics; Increased capacity in weight lifting; Increased skin thickness; Increased wound healing; Increased "energy" for life; Increased hair and nail growth. Please keep in mind that these effects are associated with a healthy life style including exercise, healthy dietary habits, and nutritional supplementation.

"We have never seen any cases of carpal tunnel symptoms, high blood sugar, glucose intolerance, or diabetes in over 700 patients in which we have monitored blood sugars. Also, we have no incidents of breast cancer, prostate cancer, or any other untoward effects. As a matter of fact, the PSA levels in men actually declined while on HGH supplementation therapy."

Anyway, we've now been using the approach for more than 20 years, and anti-aging doctors aren't finding problems. They do state that the manner of dosing is important.

I'm not sure about the study you quoted, but customarily, HGH injections were given once a week, sometimes every two weeks.

However, HGH is normally released in minute amounts about four to six times daily, so the weekly dose then was actually 28 doses given all at once. People doing injections are getting away from that.

Also, although many anti-aging doctors still do use HGH injections, most now use amino acids secretagogues. They indicate that a lot of people do not respond to injected HGH well but do respond to inducing their own levels to improve.